Serial decision-making in monkeys during an oculomotor task.

Journal of Experimental Psychology: Learning, Memory, and Cognition Metacognition in Monkeys During an Oculomotor Task

Serotonin shapes risky decision making in monkeys.

Some people love taking risks, while others avoid gambles at all costs. The neural mechanisms underlying individual variation in preference for risky or certain outcomes, however, remain poorly understood. Although behavioral pathologies associated with compulsive gambling, addiction and other psychiatric disorders implicate deficient serotonin signaling in pathological decision making, there i...

Focused Ultrasound Enhances Decision-Making in Monkeys

14 Noninvasive brain stimulation using ultrasound has many potential applications as a research 15 and clinical tool. Here, we investigated the effect of focused ultrasound (FUS) with systemically 16 administered microbubbles on perceptual decision-making behavior in monkeys. We targeted 17 FUS to the putamen in one hemisphere to open the blood-brain barrier, and then tested 18 behavioral perfo...

Oculomotor defects in cerebellectomized monkeys.

It is accepted that the cerebellum plays a role in eye movement, just as in other movement. This is because: (1) diseases of the cerebellum cause a variety of oculomotor defects' ; (2) stimulation of the cerebellum causes eye movement; (3) electric potentials appear in the cerebellum when the eyes move* ; and (4) intimate anatomic connections link cerebellum with midbrain and pontine regions im...

Ketamine-induced distractibility: An oculomotor study in monkeys.

BACKGROUND Administration of subanesthetic doses of ketamine, a noncompetitive N-methyl-D-aspartate receptor antagonist, induces a spectrum of behavioral disorders that are commonly observed in patients with schizophrenia. Although it has been demonstrated that poor antisaccade performance is a core dysfunction in schizophrenia, the ability of ketamine to induce an increased distractibility has...